Cheap bus tickets from Portland, ME to San Diego, CA

Comfort on board

Our buses are equipped with large and comfortable seats, a toilet, Wi-Fi and power outlets.

Our onboard service

Health and Safety

Keep yourself and others safe while traveling with us.

Learn more

Satisfied Customers

We've transported 100+ million happy customers worldwide. US customers give us an amazing 4.5 stars.

Read customer reviews

The Green Choice

FlixBus is one of the most eco-friendly ways to travel. Learn more about our sustainability initiatives and carbon offset programs.

Offset emissions for your trips

Bus stations and stops in Portland, ME

Please note: your ticket will contain the most up-to-date address information.

Portland (Park & Ride)

274 Marginal Way
04101 Portland
United States

View this address on Google Maps

Bus stations and stops in San Diego, CA

Please note: your ticket will contain the most up-to-date address information.

San Diego (Old Town-FlixBus)

2728 Congress St
92110 San Diego
United States

View this address on Google Maps

Bus will board at the northbound white curb at the intersection of Congress St and Telegraph Way. Telegraph way is the dirt road entrance to “Old Town San Diego.” The loading curb is in front “State Park Lot B” and is indicated by a “No Parking” sign.

San Diego (La Jolla - UC San Diego)

UCSD Health La Jolla Station
92093 San Diego
United States

View this address on Google Maps

Bus will board in the southbound bus pullout zone on Campus Point Drive immediately south of the UC San Diego Health La Jolla Blue Line Trolley Station. Look for the ‘Passenger Loading Zone 43’ sign.

San Diego (Balboa Park)

Pan American Plaza and Presidents Way
92101 San Diego, CA
United States

View this address on Google Maps

Bus will board at the tour bus loading zone located on Presidents Way near Pan American Plaza at Balboa Park (SW part of the park). ***SPECIAL OFFER***: FlixBus riders who present their ticket will receive FREE admission to the San Diego Museum of Art at Balboa Park on the day of their trip.

San Diego (Downtown/Seaport Village)

789 W Harbor Dr
92101 San Diego
United States

View this address on Google Maps

Bus will board at the curbside on W Harbor Dr adjacent to the “Headquarters at Seaport District” sign. Google Maps: https://goo.gl/maps/sTEy4a2ccMNyHMkv8

San Diego State University (Hardy Ave)

5716 Hardy Ave
92115 San Diego
United States

View this address on Google Maps

Bus will board on the westbound curbside of Hardy Ave, west of the intersection at Campanile Dr and Hardy Ave. The stop is in front of Campanile Mall.

San Diego (Old Town Transit Center-Greyhound)

4005 Taylor Street
92110 San Diego
United States

View this address on Google Maps

Bus will board at the southbound white curb on Congress St outside of the MTS Old Town Transit Center. The loading curb is along a black fence separating Congress St and the interior MTS bus boarding area.

San Diego Bus Station

1313 National Ave
92101 San Diego
United States

View this address on Google Maps

Discover all destinations

Choose from over 80 travel destinations in 11 states and growing!

Portland, ME - San Diego, CA: Quick information

Online payment

Yes

Distance

2619 miles

Direct connection

Yes

Environmentally-friendly travel?

Yes

Discover more popular bus connections

Onboard services are subject to availability