Cheap bus tickets from Des Moines, IA to Louisville, KY
from $79.99Comfort on board
Our buses are equipped with large and comfortable seats, a toilet, Wi-Fi and power outlets.
Our onboard service
Satisfied Customers
We've transported 100+ million happy customers worldwide. US customers give us an amazing 4.5 stars.
Read customer reviews
The Green Choice
FlixBus is one of the most eco-friendly ways to travel. Learn more about our sustainability initiatives and carbon offset programs.
Offset emissions for your trips
On this page
Bus stations and stops in Des Moines, IA
Des Moines
1641 E. Euclid Ave.
Des Moines, IA 50316
United States
Des Moines, IA 50316
United States
View this address on Google Maps
To view more info about this station, visit our page Des Moines
Des Moines (Subway)
1407 Buchanan St
Des Moines, IA 50316
United States
Des Moines, IA 50316
United States
View this address on Google Maps
To view more info about this station, visit our page Des Moines (Subway)
Online payment
|
Yes |
Distance
|
476 miles |
Direct connection
|
Yes |
Frequently asked questions
How long does it take to get from Des Moines to Louisville by bus?
Which destinations can I reach from Louisville with FlixBus?
Are night bus trips available from Des Moines to Louisville?
What is the distance between Des Moines and Louisville?
How can I pay for the bus from Des Moines to Louisville?
Where can I see if my bus from Des Moines to Louisville is on time?
Buses from Des Moines to Louisville
Find the cheapest buses from Des Moines to Louisville
It couldn't be easier to book your travel from Des Moines to Louisville with FlixBus - and when you book in advance, you can save money too!
FlixBus operates in 45 countries connecting 5000 destinations. So no matter where you want to go, we can take you there!
To get the cheapest tickets, book online in advance and avoid busy times like weekends and public holidays.
The distance between Des Moines and Louisville is 596 miles, which takes as little as 13 hours 50 minutes with our fastest rides.
Make your journey even easier with the FlixBus app. All your information will be saved for the next time you travel.
Taking the bus from Des Moines
Ready for your journey from Des Moines?
Des Moines is a transport hub with 2 stations and it is seriously well connected with buses to 51 destinations across the country.
No matter where you're traveling from, you can find plenty of information on our website or by contacting FlixBus directly for travel information. We'll do our best to make sure you're well-equipped for your journey, so you can experience everything the trip has to offer.
Arriving in Louisville
Start planning your trip to Louisville now. Never visited before? Here's all you need to know.
Louisville is one of the best-connected cities, so you're not short on choices of how to get here. 1 is the number of bus stations FlixBus has in Louisville, connecting 26 cities.
Never miss a beat as you sample the sights and culture synonymous with this famous city. Now is the time to hop aboard FlixBus and explore!
What to expect onboard the FlixBus bus from Des Moines to Louisville
Traveling from Des Moines to Louisville is quick, clean and comfortable - and it couldn't be easier to book a ticket. You can book online via the website, on our app, in person at a FlixShop or using Google Assistant.
We accept card payment as well as Paypal, Google Pay and Apple Pay, but there are many more payment options that you can choose from.
The easiest way to book your ticket is using our app. You'll be able to make your reservation within seconds and there's no need to print and carry the ticket with you, as your phone will be your ticket.
Want to sit beside family or friends or keep the space beside you free? Need easy access to the toilet or a table to get on with some work whilst traveling? You can reserve a seat when you book on the app or website, and you can choose from a variety of seat options including a table seat, panorama seat or extra seat.
Once you're settled in your seat, you can sit back and relax with plenty of onboard services to help you make the most of your trip. Most of our buses have onboard Wifi and an entertainment system so you can catch up on your favorite shows or listen to audiobooks. We've also got toilets onboard, as well as power outlets.
What's more, you get a generous luggage allowance when you travel with FlixBus with one carry-on bag and one checked bag, so you can bring everything you need for your trip.
Discover more popular bus connections
- Chicago, IL - Des Moines, IA
- Des Moines, IA - Chicago, IL
- Des Moines, IA - Minneapolis, MN
- Minneapolis, MN - Des Moines, IA
- Des Moines, IA - Iowa City, IA
- Iowa City, IA - Des Moines, IA
- St Louis, MO - Des Moines, IA
- Kansas City, MO - Des Moines, IA
- Des Moines, IA - Memphis, TN
- Omaha, NE - Des Moines, IA
- Des Moines, IA - St Louis, MO
- Des Moines, IA - Detroit, MI
- Fort Worth, TX - Des Moines, IA
- Des Moines, IA - Jackson, TN
- Des Moines, IA - Davenport, IA
- Wichita, KS - Des Moines, IA
- Davenport, IA - Des Moines, IA
- Des Moines, IA - Denver, CO
- Kansas City, KS - Des Moines, IA
- Des Moines, IA - Wichita, KS
- Louisville, KY - Chicago, IL
- Chicago, IL - Louisville, KY
- Louisville, KY - Cincinnati, OH
- Louisville, KY - Indianapolis, IN
- Cincinnati, OH - Louisville, KY
- Louisville, KY - Nashville, TN
- Indianapolis, IN - Louisville, KY
- Nashville, TN - Louisville, KY
- Atlanta, GA - Louisville, KY
- Detroit, MI - Louisville, KY
- Louisville, KY - Atlanta, GA
- Louisville, KY - Memphis, TN
- Louisville, KY - Columbus, OH
- Cleveland, OH - Louisville, KY
- Louisville, KY - Detroit, MI
- Memphis, TN - Louisville, KY
- Louisville, KY - Cleveland, OH
- Evansville, IN - Louisville, KY
- Louisville, KY - Evansville, IN
- St Louis, MO - Louisville, KY
Onboard services are subject to availability