Cheap bus tickets from Prague to Brussels

Find the cheapest buses from Prague to Brussels

Getting from Prague to Brussels is cheap and easy when you travel with FlixBus. The two cities are 426 miles apart and traveling between the two takes as fast as 13 hours.
FlixBus tickets are always good value, but you can save even more money by booking online in advance. Book on the website or our FlixBus App in minutes, then simply use your phone as your ticket to board the bus.
Bus tickets between Prague and Brussels cost $64.87 on average, but you can get tickets for as low as $48.99 if you book in advance and/or outside of busy travel times, like weekends and holidays. For a quick, easy and environmentally-conscious choice, travel with FlixBus.
We have a large network of 200 destinations, so you can trust us to take you from your desired departure city to your destination in comfort and style - all for great value.

Traveling from Prague to Brussels

It's easy to get from Prague to Brussels with FlixBus, with 3 direct buses per day.
It can take a minimum time of 13 hours.
Bus travel is the most environmentally friendly way to travel long distances and we're working to make it even greener with high environmental standards across our fleet of buses, the use of alternative drive and fuel technologies, and the option for all passengers to offset their carbon emissions at the point of buying a ticket.
The average cost of bus travel between Prague and Brussels is $64.87, which makes bus travel far cheaper than any other method.

Taking the bus from Prague

Traveling from Prague and not familiar with it? Here's everything you need to know.
Prague is a transport hub with 3 bus station(s); the 420 connections departing from Prague every day take travelers both within the state and further afield.

Arriving in Brussels

Traveling to Brussels for the first time? Here's what you need to know:
Brussels is very well connected to other destinations on the FlixBus network, with 185 connections arriving in one of the 2 bus station(s) of the city, giving you easy access to all corners of the country.

What to expect onboard the FlixBus bus from Prague to Brussels

Getting from Prague to Brussels aboard a FlixBus bus means traveling in comfort and style, with all the services you need to keep you occupied. Most of our buses include free Wi-Fi onboard, an entertainment system, toilets and power outlets.
You can bring one carry-on and one check-in piece of luggage per passenger, so even if you're taking a long trip, you don't need to worry about traveling light.
All ticket holders are guaranteed a seat on our buses but if you want to reserve a seat, you can do so at the time of booking. Choose from a classic seat, table seat, panorama seat or extra seat.
Just book online or on our FlixBus App when purchasing your ticket using any of our available payment methods.