Skip to main content

Cheap bus tickets from Knoxville, TN to Harrisburg, PA

from $74.99
Person using FlixBus app

Get ready!

Bus arriving in 3 mins.

Scan to download the App
Get the app and travel with ease of mind

Get live updates with push notifications and track your trip in real time. All of your travel details in one place.

android store img app store img

Comfort on the go

Kick back with free Wi-Fi, power outlets, and extra leg space. That's what modern buses are all about.

Connecting you to the world

Endless possibilities. Discover over 5,500 destinations across more than 40 countries.

Choose, book, travel

From your screen to your seat in seconds. You do the booking, we'll take care of the rest.

Planet-smart travel

Drop the car, travel with us. Increase your mileage and reduce your carbon footprint.

On this page

Bus stations and stops in Knoxville, TN

Please note: your ticket will contain the most up-to-date address information.

Discover all destinations

Choose from over 80 travel destinations in 11 states and growing!
Where to next?
Discover our travel map with over 6800 destinations worldwide.
Explore the map
Vehicle passing through a city

Frequently asked questions

The cost of a bus ticket from Knoxville to Harrisburg starts at just $79.98.
The bus journey from Knoxville to Harrisburg is 645 miles. FlixBus can get you there in 16 hours 20 minutes.
Yes, there are daily rides from Knoxville to Harrisburg.
When purchasing your bus ticket from Knoxville to Harrisburg, you can choose your preferred payment method from card, Paypal, Google Pay, and more.
Our Real-Time Bus Tracker allows you to track your bus location. Just select the relevant bus stop and check the time of arrival. This way, you can find out where your bus is and check for delays on the route.
Yes, night trip options are available from Knoxville to Harrisburg. Check out the route's schedule and choose the best option to suit your plans!
With FlixBus, you can conveniently reach 45 destinations from Harrisburg, including Pittsburgh, New York, State College.

Buses from Knoxville to Harrisburg

Find the cheapest buses from Knoxville to Harrisburg

It couldn't be easier to book your travel from Knoxville to Harrisburg with FlixBus - and when you book in advance, you can save money too! Make your journey even easier with the FlixBus app. All your information will be saved for the next time you travel.


You can pick up a bus ticket from Knoxville to Harrisburg for just $79.98 - that's way cheaper than traveling by any other method.
Buses are also a great choice for environmentally-conscious travelers. We're working towards being 100% carbon neutral and offer all travelers the opportunity to offset their carbon emissions when booking their tickets. Simply select the "CO2 compensation" box when paying online and we'll use all of the money to make a direct impact on the future of sustainable mobility.

What to expect onboard the FlixBus bus from Knoxville to Harrisburg

Traveling from Knoxville to Harrisburg is stess-free, clean and comfortable - and it couldn't be easier to book a ticket. You can book online via the website, on our app, in person at a FlixShops or at resellers.
We accept card payment as well as Paypal, Google Pay and Apple Pay, but there are many more payment options that you can choose from. The easiest way to book your ticket is using our app. You'll be able to make your reservation within seconds and there's no need to print and carry the ticket with you, as your phone will be your ticket.

Want to sit beside family or friends or keep the space beside you free? Need easy access to the toilet or a table to get on with some work whilst traveling? You can reserve a seat when you book on the app or website, and you can choose from a variety of seat options. Once you're settled in your seat, you can sit back and relax with plenty of onboard services to help you make the most of your trip. Most of our buses have onboard Wifi so you can catch up on your favorite shows, chat with your friends or listen to music and podcasts. We've also got toilets onboard, as well as power outlets.
What's more, you get a generous luggage allowance when you travel with FlixBus with one carry-on bag and one checked bag, so you can bring everything you need for your trip.

Onboard services are subject to availability