Cheap bus tickets from Tupelo, MS to Fort Myers, FL

from $152.99

Comfort on board

Our buses are equipped with large and comfortable seats, a toilet, Wi-Fi and power outlets.

Our onboard service

Health and Safety

Keep yourself and others safe while traveling with us.

Learn more

Satisfied Customers

We've transported 100+ million happy customers worldwide. US customers give us an amazing 4.5 stars.

Read customer reviews

The Green Choice

FlixBus is one of the most eco-friendly ways to travel. Learn more about our sustainability initiatives and carbon offset programs.

Offset emissions for your trips

Bus stations and stops in Tupelo, MS

Please note: your ticket will contain the most up-to-date address information.

Tupelo (M&H Quick Stop)

2611 S Eason Blvd
38804 Tupelo
United States

View this address on Google Maps

Bus stations and stops in Fort Myers, FL

Please note: your ticket will contain the most up-to-date address information.

Fort Myers South

13600 Indian Paint Ln
33912 Fort Myers
United States

View this address on Google Maps

Fort Myers-Cape Coral

4125 Cleveland Ave
33901 Fort Myers
United States

View this address on Google Maps

Bus will stop at Edison Mall Entrance D between JCPenney and Macy's. Please wait by the two benches and FlixBus sign. Restrooms are available inside Edison Mall. NO LONG-TERM OR OVERNIGHT PARKING PERMITTED. Cars parked overnight will be towed.

Ft Myers Bus Station

2250 Widman Way
33901 Fort Myers
United States

View this address on Google Maps

Discover all destinations

Choose from over 80 travel destinations in 11 states and growing!

Tupelo, MS - Fort Myers, FL: Quick information

Online payment

Yes

Distance

664 miles

Direct connection

Yes

Environmentally-friendly travel?

Yes

Discover more popular bus connections

Onboard services are subject to availability